CASE: Low grade fever and Progressive weight loss

This case is presented to us less than a year ago. Loopholes are still there and a bunch of differential diagnoses are made.

I will be enumerating the important points here:
History of Present Illness:

• easy fatigability on minimal activity
• difficulty of breathing when doing household chores
• enlarging lymph nodes in neck area
• unproductive cough
• intermittent low grade fever
• progressive weight loss

Past Medical and Personal History:

• treated for Hodgkin's lymphoma when she was 17 years old
• given MOPP chemotherapy regimen and mantle radiation therapy
• works in a paint factory for over 20 years

Physical Examination:

• in moderate respiratory distress, RR: 25/min
• HR: 120 beats/min, Temp: 37.8 Celsius
• Pale palpebral conjunctivae
• Anicteric sclerae
• (+) multiple lymph nodes on left side of neck (largest is 2cm in diameter)
• decreased breath sounds both lower lung fields
• decreased tactile and vocal fremitus
• liver palpable 3cm below right subcostal margin
• obliterated Traube's space
• pale nailbeds

Assessment?

Intervention?

Conclusion?